NuMedica Liposomal Hydroxy B12 - Steady-Release Vitamin B12 Support
Liposomal Hydroxy B12
60 Servings
by NuMedica
NuMedica Liposomal Hydroxy B12
Slow-Release, Long-Acting Form of Vitamin B12*
A liposomal vitamin B12 formula providing hydroxocobalamin for slower, steadier availability. Used when gentler, sustained B12 delivery is preferred over fast-acting formats.*
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Description*
NuMedica Liposomal Hydroxy B12™ provides vitamin B12 in the hydroxocobalamin form, delivered in a liposomal liquid designed for gradual absorption and steady availability. Vitamin B12 supports foundational processes involved in energy metabolism, nervous system function, and routine cellular activity.
This product is intended for adults who prefer a gentler B12 option or who notice they do better with sustained delivery rather than fast-acting formats.
How Hydroxocobalamin Differs From Other Forms of Vitamin B12
Vitamin B12 is available in several forms, each with distinct characteristics. Hydroxocobalamin is a naturally occurring form that the body can convert into active B12 as needed. Compared to methylcobalamin, it tends to remain in circulation longer and may have a more even effect.
This slower conversion can help support steadier B12 availability throughout the day without sharp fluctuations.
Steady Support for Energy and Nervous System Function
Vitamin B12 contributes to how the body converts food into usable energy and supports normal nerve signaling. These processes influence everyday experiences such as stamina, mental clarity, and neurological comfort.
When B12 delivery is too rapid for an individual's tolerance, some people notice restlessness or overstimulation. A slower-release option can support these systems while maintaining a calmer physiological response.
Vitamin B12 and Methylation Balance
Vitamin B12 participates in methylation-related processes that help regulate energy production, neurotransmitter activity, and cellular maintenance. These reactions occur continuously and rely on adequate availability of B12 alongside other nutrients.
Methylation functions as a foundational regulatory system within the body, influencing how metabolic demands are managed day to day, including the roles described in methylation-related cellular regulation.
How Liposomal Delivery Changes Absorption
Liposomal delivery surrounds nutrients with phospholipids that resemble components of cell membranes. This structure supports absorption while allowing nutrients to enter circulation more gradually, a pattern often associated with liposomal nutrient transport.
For individuals who have difficulty maintaining B12 levels or who prefer liquid formats, liposomal delivery offers an alternative to capsules or lozenges.
Choosing Between Vitamin B12 Options
Different B12 formats serve different needs. Some people prefer fast-acting, active forms, while others benefit from steadier delivery that prioritizes tolerance and consistency.
Vitamin B12 delivery options Methyl B-12 HP Liposomal Hydroxy B12 Form Vitamin B12 Vitamin B12 Primary active per serving Methylcobalamin Hydroxocobalamin Release style Immediate / fast-acting Slower, steadier release Adjustability Easy to add independently Useful when gentler delivery is preferred Taste / format Flavored lozenge Liposomal liquid (pump) Best for Targeted B12 support and quick availability Maintaining steadier B12 levels over time Who This Product Is Designed For
NuMedica Liposomal Hydroxy B12™ is intended for adults seeking consistent vitamin B12 support as part of a long-term wellness approach. Individual needs vary, and nutritional support works best when combined with balanced meals, manageable stress, regular movement, and adequate sleep.
This product offers a measured option for those who value stability, tolerance, and steady support over rapid effects.
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Features*
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Directions
Size: 60 Servings
Serving Size: 3 Pumps (0.5 mL)
Servings Per Container: 60
Directions: Take 3 pumps (0.5 mL) per day or as directed by your healthcare practitioner. Shake well before use.
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Ingredients
Nutrient/Ingredient Amount % Daily ValueDV 1 3 pumps (0.5 mL) Contain:
Vitamin B12 (as hydroxocobalamin) Vitamin B12
Vitamin B12 is essential for red blood cell formation, neurological function, and DNA synthesis.
1,000 mcg Proprietary Blend‡ 50 mg Lecithin (from sunflower) (non-GMO) Lecithin
Lecithin is a source of phospholipids that support brain function, liver health, and fat metabolism.
Glycerin (from sustainable palm) (kernel) Glycerin
Glycerin is a sugar alcohol used to maintain moisture in products. It supports hydration and may soothe mucous membranes.
1 The % Daily Value tells you how much a nutrient in a serving of food contributes to a daily diet. 2,000 calories a day is used for general nutrition advise. -
Questions*
Questions
If you have a question not answered on this page, please consider submitting it in the Product Questions or Feedback section in the Discussion Forum below.
What is Liposomal Hydroxy B12?
Liposomal Hydroxy B12 is a liquid vitamin B12 supplement that provides hydroxocobalamin, a form known for steadier circulation and more gradual availability compared to faster-acting B12 forms.
How is hydroxocobalamin different from methylcobalamin?
Hydroxocobalamin remains in circulation longer and is converted by the body into active B12 as needed. Methylcobalamin is already active and tends to act more quickly. Some individuals prefer hydroxocobalamin for its slower, steadier profile.
Why would someone choose a slower-release B12?
A slower-release option may be better tolerated by individuals who feel overstimulated with fast-acting B12 or who prefer more gradual nutrient support throughout the day.
What does liposomal delivery mean?
Liposomal delivery surrounds nutrients with phospholipids similar to cell membranes. This format can support absorption while allowing nutrients to enter circulation more gradually.
Does this product support energy levels?
Vitamin B12 contributes to how the body converts food into usable energy. Supporting consistent B12 availability can help maintain steadier energy rather than rapid fluctuations.
Is this product appropriate for sensitive individuals?
Some individuals who are sensitive to more immediately active B12 forms prefer hydroxocobalamin because of its gentler conversion and steadier availability.
Can this be used alongside other B vitamins?
Vitamin B12 is often used alongside other B vitamins, depending on individual needs. Some people adjust B12 separately, while others choose broader B-complex formulas.
How does vitamin B12 relate to methylation?
Vitamin B12 participates in methylation-related processes that help regulate energy metabolism, neurotransmitter activity, and cellular maintenance. Adequate B12 availability supports these ongoing pathways.
Is this intended for short-term or long-term use?
Liposomal Hydroxy B12 is designed for consistent, ongoing support as part of a long-term wellness routine rather than short-term intervention.
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Related Content*
Additional Resources
We encourage you to take advantage of these related Wellness Resources on our website.
7 Supplements to Boost MetabolismWe all know that a healthy diet and plenty of exercise are essential for staying healthy. Did you know that supplementing your diet with the right vitamins and minerals can help maintain a healthy weight? Some vitamins and minerals can even help boost our metabolism.
Liposomes - A Trojan Horse for Supplement Effectivity?Many factors are involved in how efficiently a supplement gets absorbed into the body where it is intended to go. Scientific research has shown that many tablet, capsule and liquid vitamins and supplements have an average bio-availability and absorption rate of only 5-20%. Liposomes are purported to increase the bioavailability and absorption rate by up to 80% in some cases.
Learn more about NuMedica's new line of advanced liposomal professional-grade supplements.
Nanomaterial Technology Aids Supplement AbsorptionNutrient absorption begins with digestion in the stomach. Our overall health is dependent upon the health of our immune system which resides primarily in our gut. Scientists are finding new ways to deliver the nutrients within a supplement to the targeted area of the body more efficiently. Nanotechnology appears to be a promising method to help you get the most out of your supplements, and possibly foods, which may help to improve your health.
The Importance of Vitamin B12Vitamin B12 is an essential nutrient that supports everyday functions such as energy production, nervous system health, and normal cell renewal. Because the body cannot make B12 on its own, it must come from food or, in some cases, supplementation.
What B Vitamins Actually Do - Beyond "Energy"B vitamins are often described as "energy vitamins," a phrase that appears on labels, articles, and everyday conversations. While this shorthand is familiar, it oversimplifies what B vitamins actually do in the body. Rather than producing energy directly, these nutrients support the metabolic processes that convert food into usable fuel, helping maintain steady function across daily demands.
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Product Reviews*:
5 Found
Product Reviews*
Reviews are from verified customers who purchased the product on SupplementRelief.com. They are intended to describe the quality and usefulness of the specific product i.e. "how is the product working for you?". Any benefits or results expressed are based on individual experiences that are unique, cannot be guaranteed, and have not been evaluated by the FDA. Consult with your healthcare practitioner to determine if any supplement you are considering purchasing would be a good option for your specific needs.
Phenomenal B12
on August 19, 2025
- Verified PurchaseThis is a must have in my supplement protocol. I can really tell a difference.
on July 24, 2023
- Verified PurchaseI can't go without this product. It beats shots. I started using this around Covid when I didn't have a school nurse to give me my B12. My numbers were great! Highly recommend.
Energy
on February 12, 2021
- Verified PurchaseGives me energy throughout the day. Absoloutely love.
on November 10, 2020
- Verified PurchaseI love this supplement. It tastes great and it doesn't make me jittery or anxious like methyl b12
on July 16, 2019
- Verified PurchaseEasy to take liposomal B12, good taste
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