Liposomal Tranquinox | NuMedica - Tranquinox & Tranquinox Deep
Liposomal Tranquinox
30 Servings | Regular, Deep
by NuMedica
NuMedica Liposomal Tranquinox
Powerful Support for a Healthy Sleep-Wake Cycle*
NuMedica Liposomal Tranquinox is a liquid formula combining GABA and melatonin in a single step. Available in Tranquinox and Tranquinox Deep for different routine preferences. 30 servings.*
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Description*
Multi-ingredient nighttime formula in a single step
NuMedica Liposomal Tranquinox is a liquid, liposomal formula that combines multiple ingredients commonly used in evening routines into a single product. It is designed for individuals who prefer a combined approach rather than using separate GABA or melatonin products.
This type of formula is typically chosen when a routine has multiple components and the goal is to simplify them into one consistent step before bed.
Two versions of Tranquinox
Tranquinox is available in two variations that reflect different levels of complexity within a nighttime routine:
- Liposomal Tranquinox - A simpler blend centered on GABA, melatonin, and glutathione
- Liposomal Tranquinox Deep - A broader formula that adds L-theanine, 5-HTP, botanicals, and vitamin B6
Quick way to choose
- Choose Tranquinox for a more streamlined, lighter approach
- Choose Tranquinox Deep for a more layered, comprehensive nighttime routine
Comparison
Tranquinox Tranquinox Deep Approach Simplified multi-ingredient blend Expanded, layered formula Core ingredients GABA, Melatonin, Glutathione GABA, Melatonin, 5-HTP, L-Theanine, Botanicals Complexity Lower Higher Routine style Streamlined More comprehensive Best for Simplifying multiple products More layered evening routines What makes this different
Instead of focusing on a single ingredient, Tranquinox combines several commonly used components into one formula. This changes how it fits into a routine - it replaces multiple individual products rather than adding to them.
The liposomal format delivers these ingredients in a liquid form, which differs from traditional capsules and tablets.
How it is typically used
Tranquinox is typically taken shortly before bedtime using a measured liquid serving. Because it combines multiple ingredients, it is often used as a single-step evening routine rather than alongside separate products.
Who this is typically considered for
- Preferring a combined, all-in-one nighttime formula
- Looking to simplify multiple products into one step
- Using a structured evening routine rather than single ingredients
What this is not designed to replace
This product is not intended to replace sleep habits, daily routines, or medical care. It is best understood as part of a broader evening pattern.
A combined approach to nighttime routines
Tranquinox provides a way to bring multiple commonly used ingredients together into a single, consistent step within an evening routine.
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Features*
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Directions
Size: 30 Servings
Serving Size: 6 pumps (1 mL)
Servings Per Container: 30
Directions: Take 6 pumps (1 mL) by mouth just before sleep or as directed by your healthcare practitioner. Shake well before use.
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Ingredients
Nutrient/Ingredient Amount % Daily ValueDV 1 6 Pumps (1 mL) Contain:
Proprietary Blend 10 mg GABA Gamma Aminobutyric Acid GABA
GABA is a neurotransmitter that promotes relaxation, reduces mental stress, and supports restful sleep and balanced mood.
Melatonin Melatonin
Melatonin is a hormone that regulates sleep-wake cycles, supporting restful sleep and circadian rhythm alignment.
Glutathione Glutathione
Glutathione is the body?s master antioxidant that supports detoxification, immune defense, and cellular protection from oxidative stress.
1 The % Daily Value tells you how much a nutrient in a serving of food contributes to a daily diet. 2,000 calories a day is used for general nutrition advise. -
Questions*
Questions
If you have a question not answered on this page, please consider submitting it in the Product Questions or Feedback section in the Discussion Forum below.
What is Liposomal Tranquinox typically used for?
Liposomal Tranquinox is typically used as a single-step evening routine that combines multiple ingredients, rather than using separate GABA or melatonin products.
How is this different from taking GABA or melatonin alone?
Single-ingredient products are used individually, while Tranquinox combines several commonly used components into one formula, simplifying the routine.
What is the difference between Tranquinox and Tranquinox Deep?
Tranquinox provides a more streamlined blend centered on GABA and melatonin, while Tranquinox Deep includes additional ingredients such as L-theanine, 5-HTP, and botanicals for a more layered approach.
When would someone choose the Deep version?
The Deep version is typically chosen when a more comprehensive, multi-ingredient routine is preferred rather than a simpler formulation.
How is this taken?
It is typically taken as a measured liquid serving using the pump system shortly before bedtime.
Can this replace other nighttime supplements?
Some individuals use it as a single product instead of combining multiple separate supplements, depending on how their routine is structured.
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Related Content*
Additional Resources
We encourage you to take advantage of these related Wellness Resources on our website.
Liposomes - A Trojan Horse for Supplement Effectivity?Many factors are involved in how efficiently a supplement gets absorbed into the body where it is intended to go. Scientific research has shown that many tablet, capsule and liquid vitamins and supplements have an average bio-availability and absorption rate of only 5-20%. Liposomes are purported to increase the bioavailability and absorption rate by up to 80% in some cases.
Learn more about NuMedica's new line of advanced liposomal professional-grade supplements.
Nanomaterial Technology Aids Supplement AbsorptionNutrient absorption begins with digestion in the stomach. Our overall health is dependent upon the health of our immune system which resides primarily in our gut. Scientists are finding new ways to deliver the nutrients within a supplement to the targeted area of the body more efficiently. Nanotechnology appears to be a promising method to help you get the most out of your supplements, and possibly foods, which may help to improve your health.
The Most Effective Ways to Deal With Stress Weight LossCurrently, three-quarters of Americans experience moderate to high levels of stress. In small doses, periodic stress can be good. Stress can improve motivation, resilience, and cognitive function.
Webinar: Better Sleep Tonight!Facilitator Libby Wright interviews Dr. Jamie Wright who discusses the role of sleep in weight loss with participants of the Your Best Weight online education program. Dr. Wright is a board certified physician with a Masters Degree in Metabolic and Nutritional Medicine. The webinar last for 29 minutes and addresses questions submitted by the program participants.
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Product Reviews*:
32 Found
Product Reviews*
Reviews are from verified customers who purchased the product on SupplementRelief.com. They are intended to describe the quality and usefulness of the specific product i.e. "how is the product working for you?". Any benefits or results expressed are based on individual experiences that are unique, cannot be guaranteed, and have not been evaluated by the FDA. Consult with your healthcare practitioner to determine if any supplement you are considering purchasing would be a good option for your specific needs.
Deep sleep
on April 13, 2026
- Verified PurchaseI usually fall asleep@ least 4 hrs. 5 nights per wk.
sleep
on March 12, 2026
- Verified Purchasesleep restful.
on February 8, 2026
- Verified PurchaseI USE TRANQUINOX DEEP TO HELP ME SLEEP. I USE HALF THE DOSE EARLY OVER NIGHT THEN WHEN I WAKE UP A COUPLE HOURS LATER TO USE THE BATHROOM I TAKE THE OTHER HALF DOSE. IT IS NOT 100% EFFECTIVE EVERY TIME BUT DEFINITELY HELPS.
sleep
on November 24, 2025
- Verified Purchaseusually works for sleeping.
on October 2, 2025
- Verified PurchaseThumbs Up! Stress Relief in a Squirt!
Works great!
on June 22, 2025
- Verified PurchaseThis has helped me sleep like nothing else. It's fabulous
deep
on April 29, 2025
- Verified PurchaseMost nights I sleep w/ use of product.
NuMedica Liposomal Tranquinox
on April 10, 2025
- Verified PurchaseI would highly recommend! This is real relief after over 25 years of various strategies to get some good sleep with no success. Also after many years of prescription medications, which have horrible side effects.
Best sleep aid
on February 22, 2025
- Verified PurchaseLiposomal Tranquinox Deep is the best sleep aid I've ever tried. It's quick, effective and doesn't leave you groggy in the morning. The folks at Supplement Relief are wonderful to deal with, very helpful and go out of their way to deliver a great customer experience.
Great product and Comoany
on January 14, 2025
- Verified PurchaseRecommended by my ND
Did Not Work
on October 2, 2024
- Verified PurchaseThis helped me fall asleep, but I was awake after a couple of hours. It's disappointing that your return policy doesn't reflect your support of the product.
Helps for 6 hours
on June 6, 2024
- Verified PurchaseI've used the product before. As usual, the product worked great for a while and then not so much as my body got used to it. But since I haven't used it for a long time I'm going to try it again for stressful nights.
Tranquinox Works!!
on August 9, 2023
- Verified PurchaseI have been using Tranquinox Deep for a couple of months now. This sleep aide has worked for me, and I have had sleep issues for many years.
on June 21, 2023
- Verified Purchaseit is what cure my imsomnia on 10 months
Satisfied and happy
on June 12, 2023
- Verified PurchaseI used to sleep only 4-5 hours daily and with this product so far I am up to 7 hours.
I know I will fall asleep
on April 9, 2023
- Verified PurchaseWorks.
on April 10, 2021
- Verified PurchaseHelps most night in getting me to fall asleep and stay asleep .
on March 22, 2021
- Verified Purchasewas skeptical but the friend that recommended it said just try it. It really works I go to sleep and sleep all night with no drug hangover!!!
Great Product
on March 8, 2021
- Verified PurchaseThis is a great product! It is our product of choice for sleepless nights.
on January 17, 2021
- Verified PurchaseIt helps keep me asleep as long as I need to be without frequent interrupts
Finally
on November 20, 2020
- Verified PurchaseA safe sleep aid that actually works!
Mrs. Terri Pearsons
on November 5, 2020
- Verified PurchaseWorks fast. Though I don't always sleep through the night taking Tranquinox makes it happen more often.
on July 23, 2020
- Verified PurchaseHelps with sleep and anxiety
on May 15, 2020
- Verified PurchaseI have anxiety and depression since 2012 and Tranquinox is like magic! I take 6 sprays when I get into bed and i can't keep my eyes open after about 20 mins. or so AND I only wake up once instead of 3 times AND I go right back to sleep. I mean it's been a miracle for me!
Too soon
on April 22, 2020
- Verified PurchaseI just started taking the supplements so it's too soon to notice a difference. No difference and lack of sleep the first three nights of taking this product
on April 9, 2020
- Verified PurchaseWorks well and no grogginess
Great supplement
on March 27, 2020
- Verified PurchaseMy doctor recommended this product for my anxiety and difficulty sleeping. It has been working well and I will continue to take this product as it is a natural alternative to medication.
Ahhh Sleep
on March 18, 2020
- Verified PurchaseOnly use about 1/2 the recommended dosage, but within 30 minutes I'm falling asleep and stay asleep for hours - yet wake up without that drowsy feeling from prescription sleep-aids.
on February 2, 2020
- Verified PurchaseI sleep like a baby on this product. Have no trouble falling asleep and i stay asleep each night for full eight hours of sleep. Highly recommend!
on November 10, 2019
- Verified PurchaseI am so grateful for this product. It has brought peaceful, non-drugged sleep.
In Need of REST?
on September 9, 2019
- Verified PurchaseI have been struggling with insomnia - Tranquinox has helped me without side effects. There are many products out for sleep, but they are dangerous; you may not know the harm they are doing. I am resting now and not worrying! Thank you NuMedica!
on August 22, 2019
- Verified Purchaseworks great
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Liposomal GABAGamma Aminobutyric Acid (GABA), 250 mg*
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60 LozengesNuMedica Melatonin Lozenges provide 3 mg of melatonin in a fast-dissolving format, commonly used in routines focused on sleep timing and evening use. 60 lozenges.*Gluten Free VegetarianSKU: NM119 - UPC: 812527011199
3 mg Peppermint Lozenges to Support the Sleep Cycle*NuMedica Melatonin Lozenges provide 3 mg of melatonin in a fast-dissolving format, commonly used in routines focused on sleep timing and evening use. 60 lozenges.*
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Cognitive Function & Memory*NuMedica Phosphatidyl Serine is a sunflower-derived phospholipid used in routines focused on cognitive function and mental clarity. Includes 60 capsules.*
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I originally purchased a bottle of this on the advice of my doctor (they sell them at her office), and it works AMAZINGLY well. Since her office is quite a drive for me, I decided to order from Supplement Relief. My Tranquinox arrived about a week later and I'm back to having a fantastic night's sleep. SO glad I found you folks!
I purchased two bottles and am having trouble with the pump on both of them. I have primed them and tried turning the head of the pump and still haven't had any luck with getting consistent sprays. The pump on these two bottles is different than my previous bottle.
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