Nitric Oxide Vascular Assist

NOVA Complete boosts nitric oxide production for enhanced circulation in men and women.^*

NOVA Complete is designed to increase nitric oxide production in the body.* Instead of relying on L-arginine like most formulas, it features a superior combination of L-citrulline, select botanicals, and key vitamins and minerals to boost nitric oxide, relax blood vessels, and enhance circulation in men over 40.^*

L-Citrulline is an amino acid converted to L-arginine, then nitric oxide in the kidneys. Nitric oxide helps relax blood vessels, which may improve blood circulation in all body parts, including the heart and reproductive organs. L-citrulline increases arginine production in a way that may be more efficient than taking arginine itself.^*

Grapeseed extract is derived from the pulverized seeds of red wine grapes. Like L-citrulline, grapeseed extract may help boost nitric oxide and has a proven track record for maintaining healthy blood pressure.^*

Why Arginine Free?

L-Citrulline serves as an L-arginine precursor, but the body constantly converts the two amino acids back and forth. There is a limit to how much arginine can circulate in the liver, but there's no such limit for citrulline. This may be why animal studies indicate that supplementing with citrulline is a more efficient way to keep arginine and nitric oxide stores at optimal levels.^* Because arginine breaks down quickly, citrulline provides a more long-lasting effect, especially for men over 40.^*

Supplemental citrulline has proven effective at raising levels of nitric oxide synthase - a group of enzymes that catalyze nitric oxide production - and keeping blood pressure within normal limits in a placebo-controlled human trial.*8 In another study, participants who drank watermelon juice, rich in citrulline, were also better able to maintain blood pressure within healthy limits.^*

Nitric Oxide, Sexual Performance, and Blood Pressure

In 1998, three scientists won a Nobel Prize for their work demonstrating that nitric oxide may help relax the endothelial tissue in the lining of blood vessels, which may improve blood circulation.^* Better circulation has two key benefits for men over 40: It may help maintain normal blood pressure and may improve sexual performance.^*

Botanical Blend

To reinforce the actions of L-citrulline, NOVA Complete also includes a quartet of heart-healthy botanicals: grapeseed extract, hawthorn extract, green coffee bean extract, and beet powder.

All four botanicals share a similar mechanism of action: They enhance the release of nitric oxide from the endothelial tissue in the lining of blood vessels, helping them to relax.^*

Grapeseed extract:

Human research on grape-seed extract, including a meta-analysis of studies, has found it may help maintain blood pressure within normal limits.^* It is especially effective for heavyset people or those with sluggish metabolisms.^* Grapeseed extract also improves circulation, as evidenced by the fact that it reduced leg swelling in a study of sedentary, healthy young women.^*

Hawthorn extract:

Hawthorn has a history of use for cardiovascular health dating back to antiquity. Many human trials have shown it supports both heart and blood vessel health.^* Hawthorn has improved exercise tolerance, shortness of breath, energy levels, and subjective perceptions of heart health.^*

Green coffee bean extract:

Green coffee bean extract is rich in chlorogenic acids, potent antioxidants that reduce oxidative stress on the vascular endothelium.* It has been found in placebo-controlled research to support vasoreaction (the ability of blood vessels to dilate) and to maintain blood pressure already within normal limits.^*

Beet root powder:

Consumption of nitrate-rich foods is linked to better cardiovascular health and enhanced athletic performance.^* This is likely because intestinal flora converts nitrates to nitrite and nitric oxide. Beet juice and beet powders are especially popular with athletes because beets are a noted source of dietary nitrates.^*

Key Vitamins and Minerals

NOVA Complete rounds out its formula with several blood pressure-friendly nutrients, such as vitamin C, magnesium, and zinc.* All three play a role in the release of nitric oxide.^*

Vitamin C (from amla fruit extract)

A study of 914 older British adults found those with higher blood levels of vitamin C were better able to maintain blood pressure within normal limits than those with lower levels.* Their pulse rates were also lower.^* Another large observational study of 1,860 adults aged 45 to 75 had similar findings.^*

Magnesium (bisglycinate)

Observational studies indicate people with a higher dietary magnesium intake are more likely to have a healthy blood pressure than those with a lower intake.^* Unfortunately, up to half Americans eat a magnesium-deficient diet.^*

Zinc (glycinate)

Multiple observational studies have found that both higher dietary intake of zinc and higher blood levels of zinc are linked to healthy blood pressure.^* Zinc absorption declines with age, so as many as 40 percent of seniors may be deficient in this mineral.^*