NuMedica Mitochondrial Recharge® supports ATP production and mitochondrial efficiency with amino acids, antioxidants, and minerals for lasting energy and vitality.*
NuMedica Mitochondrial Recharge® is a targeted formula designed to help restore the body's ability to produce clean, efficient energy at the cellular level. It combines amino acids, minerals, and antioxidants that fuel the mitochondria-the tiny "power plants" within each cell responsible for creating adenosine triphosphate (ATP), the body's energy currency.*
Every heartbeat, muscle contraction, and mental task depends on healthy mitochondria. Over time, stress, toxin exposure, poor nutrition, and aging can reduce mitochondrial efficiency. When this happens, energy production slows, and symptoms like fatigue, sluggish recovery, and cognitive fog can appear. Supporting these energy systems helps restore cellular vitality and overall resilience. For a deeper look at how mitochondria influence daily energy and health, see this overview of mitochondrial function.
Mitochondrial Recharge® provides the nutritional framework for rebuilding energy production at its source. It supplies key cofactors that drive the mitochondrial processes responsible for ATP generation and antioxidant protection. Nutrients such as acetyl-L-carnitine, alpha-lipoic acid, and N-acetyl-L-cysteine (NAC) help transport fuel into the mitochondria and maintain the redox balance required for efficient metabolism.*
Coenzyme Q10-available in complementary formulas like CoQ-Clear® 100 Ubiquinone and CoQ-Clear® 100 Ubiquinol-acts as the electron carrier within the mitochondrial respiratory chain, linking nutrient metabolism to usable energy. When combined with antioxidants such as resveratrol and turmeric, these nutrients help preserve mitochondrial structure and function under oxidative stress.*
Together, these compounds reinforce the body's natural capacity to produce energy cleanly and efficiently, supporting endurance, cognitive focus, and long-term metabolic health. This foundational approach complements advanced longevity formulas like MitoSpark™, which emphasize mitochondrial renewal and turnover through autophagy and mitophagy.*
Mitochondrial Recharge® focuses on rebuilding the nutrient and cofactor systems that sustain energy production. MitoSpark™ extends that foundation by promoting mitochondrial renewal and longevity through cellular cleanup and regeneration. The table below outlines how they differ and work together as part of a complete mitochondrial care strategy.*
| Feature | Mitochondrial Recharge® | MitoSpark™ |
|---|---|---|
| Primary Focus | Restores ATP energy production and antioxidant protection | Promotes autophagy and mitophagy for cellular renewal and longevity |
| Key Mechanism | Supplies cofactors (Carnitine, CoQ10, ALA, NAC) to fuel mitochondria directly | Encourages mitochondrial turnover via Urolithin A, Spermidine, and polyphenols |
| Formula Base | Amino acids, antioxidants, and minerals | Botanical extracts and longevity compounds |
| Ideal For | Fatigue, brain fog, recovery, and cardiovascular support | Healthy aging, long-term energy resilience, and metabolic balance |
| Complementary Use | Pairs well with Foundation Essentials for daily nutrition | Pairs well with Mitochondrial Recharge® for comprehensive mitochondrial care |
For best results, combine NuMedica Mitochondrial Recharge® with steady, sustainable lifestyle habits that keep your energy systems functioning efficiently. Eating real, nutrient-dense foods fuels your cells with the materials they need. Regular movement strengthens your body and supports circulation. Breathing with intention calms stress and aids recovery. Clear, steady thinking helps you maintain balance and consistency. These behaviors-outlined in the Four Foundations of Wellness-create the conditions your mitochondria need to thrive. Supporting these basics with adequate hydration, restorative rest, and minimal toxin exposure further enhances the body's ability to produce clean, steady energy.*
Size: 90 Vegetable Capsules
Serving Size: 3 Capsules
Servings Per Container: 30
Directions: Take three capsules once per day or as directed by your healthcare practitioner.
| Nutrient/Ingredient | Amount | % Daily ValueDV 1 |
|---|---|---|
|
Biotin
Biotin
Biotin is a B vitamin (B7) essential for carbohydrate metabolism, skin, hair, and nail health. It also supports nervous system function. |
200 mcg | |
|
Zinc (as zinc bisglycinate chelate)†
Zinc
Zinc is a trace mineral that supports immune function, wound healing, and DNA synthesis. |
35 mg | |
|
Acetyl L-Carnitine hydrochloride
Acetyl L-Carnitine
Acetyl L-Carnitine is a form of carnitine that crosses the blood-brain barrier and supports cognitive function, energy metabolism, and mitochondrial health. |
300 mg | |
|
L-Ornithine hydrochloride
L-Ornithine
L-Ornithine is involved in the urea cycle and supports ammonia detoxification, athletic recovery, and growth hormone release. |
300 mg | |
|
Alpha Lipoic Acid
Alpha Lipoic Acid
Alpha Lipoic Acid is a potent antioxidant that supports metabolic health, blood sugar regulation, and cellular energy production. It also helps regenerate other antioxidants. |
200 mg | |
|
N-Acetyl Cysteine
N-Acetyl Cysteine
N-Acetyl Cysteine is a precursor to glutathione and supports detoxification, respiratory health, and antioxidant defense. |
200 mg | |
|
Quercetin
Quercetin
Quercetin is a flavonoid that supports immune health, histamine response, and antioxidant defense. |
200 mg | |
|
Arginine alpha-ketoglutarate (AAKG)
Arginine alpha-ketoglutarate
Arginine alpha-ketoglutarate is a compound used to support nitric oxide production, circulation, and muscle performance. It?s often included in sports and recovery formulas. |
100 mg | |
|
L-Citrulline
L-Citrulline
L-Citrulline is an amino acid that supports nitric oxide production, circulation, and exercise performance by reducing fatigue and muscle soreness. |
100 mg | |
|
L-Methionine
L-Methionine
L-Methionine is a sulfur-containing essential amino acid that supports detoxification, liver health, and antioxidant synthesis. |
100 mg | |
|
Japanese Knotweed (Polygonum cuspidatum) extract
Japanese Knotweed
Japanese Knotweed is a plant source of resveratrol, supporting cardiovascular, cellular, and inflammatory health. |
75 mg | |
|
Turmeric Extract (Curcuma longa) (rhizome) (95% curcuminoids)
Turmeric Extract
Turmeric Extract contains curcuminoids that support inflammation control and antioxidant defense. |
50 mg | |
|
Coenzyme Q10 (ubiquinone)
Coenzyme Q10
Coenzyme Q10 is a powerful antioxidant that supports mitochondrial energy production, heart function, and overall cellular vitality. |
45 mg | |
| 1 The % Daily Value tells you how much a nutrient in a serving of food contributes to a daily diet. 2,000 calories a day is used for general nutrition advise. | ||
If you have a question not answered on this page, please consider submitting it in the Product Questions or Feedback section in the Discussion Forum below.
It's ideal for adults experiencing low energy, muscle fatigue, or mental sluggishness, and for anyone looking to support overall vitality through mitochondrial health.
Yes. Many practitioners recommend starting with NuMedica Mitochondrial Recharge® to rebuild cellular energy, then adding MitoSpark™ for long-term mitochondrial renewal and longevity support.
Mitochondrial support works best as part of a steady, long-term wellness routine. Many practitioners view consistent use as part of ongoing cellular maintenance rather than a short-term boost. The goal is to help your body maintain efficient energy production and resilience over time.
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Oxidative stress is a natural process that occurs when there is an imbalance of free radicals to antioxidants in the body, which ultimately causes damage to its cells and tissues. Oxidative stress is a natural process in aging, though long-term oxidative stress leads to chronic disease.
Coenzyme Q10 (CoQ10) is a naturally occurring compound that plays a critical role in cellular energy production and antioxidant defense. Found in every cell of the body, particularly in energy-demanding organs such as the heart and liver, CoQ10 supports mitochondrial function and helps protect against oxidative stress. As we age or face increased metabolic demands, CoQ10 levels decline - making supplementation an effective way to support cardiovascular and overall health.*
Reviews are from verified customers who purchased the product on SupplementRelief.com. They are intended to describe the quality and usefulness of the specific product i.e. "how is the product working for you?". Any benefits or results expressed are based on individual experiences that are unique, cannot be guaranteed, and have not been evaluated by the FDA. Consult with your healthcare practitioner to determine if any supplement you are considering purchasing would be a good option for your specific needs.
We have used this in our family. Our Doctor recommended it. It's a great product that helps cellular health. Thank you for mailing it so quickly.
This product is excellent got the Mitochondria. Our dr recommended it.
A naturopath put me on this product because I have a bump on my tongue that would flare up and swell, get so sore it was hard to chew food. Since being on this it has not flared up again, it's been about 10 months. It was happening every couple of weeks prior to using this product. Amazing and I order it on my own now.
This product helps recharge cells and to help with energy.
This product is a miracle with rapid increase in energy and overall well-being. Has saved me several times. Great for stress and following illness. No need to take on regular basis but as needed.
I have not tried it yet but a friend that also had hair loss due to covid pneumonia states it worked to improve the health of her hair.
This stuff is amazing. I feel so much better than a couple months ago. Great product!
Helps with focus and memory
Seems to be helping
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I am interested in purchasing Microcondial Recharge But I would like to see list of ingredients in this products I cannot see it on bottle package thank you
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