NuMedica Methyl B-12 HP - High-Potency Active Vitamin B12 Lozenges
Methyl B-12 HP
60 Lozenges
by NuMedica
NuMedica Methyl B-12 HP
Supports Healthy Homocysteine Levels*
A high-potency vitamin B12 formula providing methylcobalamin in a lozenge format. Used when targeted, active B12 support is preferred without additional methylation nutrients.*
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Description*
NuMedica Methyl B-12 HP™ Lozenges provide vitamin B12 in its active form, methylcobalamin, to support everyday nervous system function, energy metabolism, and cardiovascular balance. Vitamin B12 plays a steady role in how the body uses nutrients, maintains neurological function, and supports routine cellular activity.
This product is typically chosen by adults who want targeted vitamin B12 support without adding additional methylation or B-complex nutrients.
Who Methyl B-12 HP Is Intended For
Methyl B-12 HP is often used in situations such as:
- Wanting focused vitamin B12 support rather than a multi-nutrient formula
- Preferring an active form of B12 that the body can use directly
- Supporting everyday energy, focus, and nervous system comfort
- Maintaining consistent B12 intake as part of a long-term routine
- Adjusting B12 intake independently from other B vitamins
In these cases, a single-nutrient B12 formula allows for clarity and flexibility.
What This Formula Is Not Meant to Replace
Methyl B-12 HP is not intended to replace medical care, address diagnosed neurological conditions, or function as a complete methylation or B-complex formula. It does not provide folate, vitamin B6, or other nutrients involved in broader methylation support.
This product serves as a focused option within vitamin B12 support rather than a system-level approach.
Why the Active Form of Vitamin B12 Is Used
Vitamin B12 supports routine metabolic processes related to energy production, nervous system signaling, and normal cell renewal. Because the body cannot produce B12, intake depends on diet or supplementation.
Methylcobalamin is the active form of vitamin B12 and can be used directly by the body without requiring conversion. This can be relevant when the efficiency of B12 handling varies.
Vitamin B12, Homocysteine, and Methylation
Vitamin B12 works alongside folate and vitamin B6 to support normal homocysteine metabolism. Homocysteine is a natural byproduct of protein metabolism that the body routinely processes as part of cardiovascular and cellular maintenance.
These reactions occur within broader methylation pathways that support everyday energy balance, neurotransmitter function, and cellular repair.
How Methyl B-12 HP Compares to Related Options
The options below represent the most common comparison points for individuals considering targeted vitamin B12 support.
Vitamin B12 Delivery Options Methyl B-12 HP Liposomal Hydroxy B12 Form Vitamin B12 Vitamin B12 Primary active per serving Methylcobalamin Hydroxocobalamin Release style More immediate availability Slower, steadier delivery Adjustability Easy to use independently Often chosen when gentler delivery is preferred Taste / format Flavored lozenge Liposomal liquid Best for Targeted B12 support Maintaining steadier B12 levels When a Different Option May Make Sense
Some individuals prefer a broader methylation formula when multiple nutrients need attention at once. Others choose different B12 forms when delivery method or tolerance is the primary concern.
Methyl B-12 HP is most often selected when active, standalone vitamin B12 support is the goal.
A Focused Approach to Vitamin B12 Support
NuMedica Methyl B-12 HP™ Lozenges are designed to fit into a long-term wellness routine that values consistency and clarity. The lozenge format offers a practical way to support vitamin B12 intake without unnecessary complexity.
This product reflects a restrained, single-nutrient approach for individuals who want precise control over their B12 support.
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Features*
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Directions
Size: 60 Lozenges
Serving Size: 1 Lozenge
Servings Per Container: 60
Directions: Chew one lozenge once per day until dissolved or as directed by your healthcare practitioner.
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Ingredients
Nutrient/Ingredient Amount % Daily ValueDV 1 Vitamin B12 (as methylcobalamin) Vitamin B12
Vitamin B12 is essential for red blood cell formation, neurological function, and DNA synthesis.
5,000 mcg One Lozenge Contains:
1 The % Daily Value tells you how much a nutrient in a serving of food contributes to a daily diet. 2,000 calories a day is used for general nutrition advise. -
Questions*
Questions
If you have a question not answered on this page, please consider submitting it in the Product Questions or Feedback section in the Discussion Forum below.
What is methylcobalamin?
Methylcobalamin is the active form of vitamin B12 that the body can use directly. Unlike some other forms, it does not require additional conversion before participating in routine metabolic and neurological processes.
How is this different from regular vitamin B12?
Vitamin B12 supplements are available in several forms. Methyl B-12 HP™ provides methylcobalamin, which is already active. Other forms, such as cyanocobalamin, must be converted by the body before they can be used.
Why does vitamin B12 matter for everyday health?
Vitamin B12 supports normal energy metabolism, nervous system function, and cellular activity. It plays a role in how the body uses nutrients and helps maintain mental clarity and neurological comfort over time.
What does vitamin B12 have to do with homocysteine?
Vitamin B12 works together with folate and vitamin B6 to support normal homocysteine metabolism. Homocysteine is a natural byproduct of protein metabolism that the body routinely processes as part of cardiovascular and cellular maintenance.
Is this product the same as a methylation supplement?
No. Methyl B-12 HP™ is a single-nutrient product that provides only active vitamin B12. While B12 participates in methylation-related pathways, this formula does not supply the full range of nutrients involved in those processes.
Who might prefer a B12-only product instead of a combination formula?
Some individuals prefer to adjust one nutrient at a time rather than using a broader formula. A B12-only option can be useful when folate or other B vitamins are already being used separately or are not currently needed.
Why is this product a lozenge instead of a capsule?
The lozenge format allows the tablet to dissolve slowly in the mouth, which many people find convenient. Some individuals also prefer lozenges when swallowing capsules is difficult.
Can this product be used long term?
Vitamin B12 is a water-soluble nutrient involved in ongoing metabolic activity. Long-term use is common when dietary intake is inconsistent, though individual needs can change over time.
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Related Content*
Additional Resources
We encourage you to take advantage of these related Wellness Resources on our website.
High Cortisol and Strategies to Reduce Symptoms of Chronic StressCortisol, often called the "stress hormone," plays an important role in the body's response to stress. The adrenal glands produce cortisol, essential for maintaining the body's systems and regulating various physiological processes. While cortisol is important for survival, chronically high levels can harm physical and mental health.
Methylation Explained Without the Biochemistry DegreeMethylation is a word that appears often in discussions about genetics, B vitamins, and stress, yet it is rarely explained in everyday terms. Rather than being a single switch or isolated pathway, methylation refers to a set of ongoing processes that help the body regulate, communicate, and adapt. Understanding it does not require advanced science; it only requires a clear view of how coordination works within living systems.
What "Adrenal Stress" Means in Everyday TermsThe phrase "adrenal fatigue" is commonly used to describe a pattern of ongoing exhaustion, low stress tolerance, and slow recovery that does not improve with rest alone. While the term is familiar, it is not a medical diagnosis. Instead, it reflects how people experience prolonged stress and its effects on energy, focus, and resilience across daily life.
What B Vitamins Actually Do - Beyond "Energy"B vitamins are often described as "energy vitamins," a phrase that appears on labels, articles, and everyday conversations. While this shorthand is familiar, it oversimplifies what B vitamins actually do in the body. Rather than producing energy directly, these nutrients support the metabolic processes that convert food into usable fuel, helping maintain steady function across daily demands.
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Product Reviews*:
14 Found
Product Reviews*
Reviews are from verified customers who purchased the product on SupplementRelief.com. They are intended to describe the quality and usefulness of the specific product i.e. "how is the product working for you?". Any benefits or results expressed are based on individual experiences that are unique, cannot be guaranteed, and have not been evaluated by the FDA. Consult with your healthcare practitioner to determine if any supplement you are considering purchasing would be a good option for your specific needs.
on July 24, 2025
- Verified PurchaseDelicious tasting
Frequent User
on January 26, 2024
- Verified PurchaseI struggled for years with low B-12. When Covid hit, I no longer had easy access to B=12 injections. When I began using the Methyl B-12 HP, my numbers were higher than with injections. My provider enthusiastically said, "Keep doing what you are doing!" This is definitely the better way to improve my Vitamin B health.
Doctor Recommended This
on February 19, 2023
- Verified PurchaseMy doctor recommended this product for my MTHFR mutation. I love this product and this company is great to order from.
Lost without it
on September 4, 2021
- Verified PurchaseThis supplement has made such a difference for me. I was feeling foggy and slow all the time and feared for my mental health. Then i learned about these and started taking them right away. After about a month i
on June 10, 2021
- Verified PurchaseHelps with neuropathy
Great Supplement
on February 15, 2021
- Verified PurchaseMy Dr. put me on this supplement following a gruesome chemotherapy treatment. I immediately felt better
on January 21, 2021
- Verified PurchaseHappy with the results of using this product, returning customer
on September 28, 2020
- Verified PurchaseExcellent product for your B12 needs
on August 8, 2020
- Verified PurchaseGreat
Methyl B-12
on December 12, 2019
- Verified PurchaseThis product gives me energy that I lack
on September 5, 2019
- Verified PurchaseFeels like this product has replaced something that was missing in my body that I need since I have trouble processing methyl b 12
Great product
on July 27, 2019
- Verified PurchaseI like this specific brand it works for me I highly recommend it
on December 12, 2018
- Verified PurchaseGives me a little more energy and I seem to sleep better and handle stress better.
Energy!
on February 19, 2018
- Verified PurchaseHelps to increase my energy levels.
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