NuMedica HiFlora-50₁₂ is a high-potency probiotic blend featuring 12 complementary strains and 50 billion CFU per serving to support everyday microbial balance, digestive comfort, and immune resilience. *
NuMedica HiFlora-50₁₂ is a high-potency, multi-strain probiotic formulated to support everyday digestive comfort, microbial balance, and immune resilience. Each serving provides 50 billion CFU† across 12 complementary strains, including a spore-forming Bacillus subtilis that remains stable through the upper digestive tract. This broad-spectrum structure reflects the role that multi-strain formulas can play in supporting diverse microbial functions, as outlined in discussions of how different probiotic designs serve different needs. HiFlora-50₁₂ offers steady, comprehensive support for individuals seeking a well-rounded approach to maintaining a healthy intestinal environment.
The strains in HiFlora-50₁₂ work across different regions of the GI tract to encourage a calm, balanced microbial community. Lactobacillus and Bifidobacterium species help support regularity, comfortable digestion, and a stronger intestinal barrier. The inclusion of Bacillus subtilis DE111® adds durability, as its spore-forming nature allows it to withstand harsh conditions until it reaches the gut, where it can contribute to microbial diversity.
This formula is designed with practicality in mind: delayed-release capsules help protect the organisms during transit, and the desiccant-lined bottle helps maintain potency through the expiration date. For individuals seeking a single probiotic that supports many aspects of digestive and immune function, HiFlora-50₁₂ offers a dependable daily option.
HiFlora-50₁₂ is well suited for adults seeking a broad-spectrum, higher-potency probiotic to support overall digestive well-being or times of increased lifestyle stress. Its diverse strain profile may be useful for those who prefer one comprehensive formula rather than rotating between narrower, situation-specific options. A practitioner can help determine whether a higher-dose, multi-strain approach aligns with your health history and goals.
NuMedica offers several probiotic formulas that differ in organism type, CFU level, and intended use. HiFlora-50₁₂ serves as the broadest option, while Tri-Flora Plus™ combines Saccharomyces boulardii with select bacteria, and SacBoulardii™ provides a single-organism yeast for more targeted support. The table below outlines these distinctions so you can compare structure, purpose, and practical fit.
| Feature | HiFlora-50₁₂ | Tri-Flora Plus™ | SacBoulardii™ |
|---|---|---|---|
| Primary Focus | Broad, multi-strain bacterial support for overall microbial balance | Combination of Saccharomyces boulardii with select Lactobacillus and Bifidobacterium | Focused support using a single DNA-verified Saccharomyces boulardii strain |
| Organisms Included | 12 bacterial strains, including Lactobacillus, Bifidobacterium, and Bacillus subtilis | SB + 3 bacterial strains | SB only |
| Potency | 50 billion CFU† per serving | 5 billion live organisms per capsule | Single-organism yeast; CFU not emphasized |
| Key Distinguishing Features | High diversity; includes spore-forming DE111®; delayed-release capsules | Resilient strains suitable for changing GI environments | Dairy-free, lactose-free, DNA-verified strain specificity |
| Best For | Comprehensive daily probiotic support and broader digestive needs | Situational or moderate-level support where yeast + bacteria may be helpful | Targeted Saccharomyces boulardii support under practitioner guidance |
Size: 60 Vegetable Capsules
Serving Size: 2 Capsules
Servings Per Container: 30
Directions: Take two capsules once per day or as directed by your healthcare practitioner.
| Nutrient/Ingredient | Amount | % Daily ValueDV 1 |
|---|---|---|
| High Potency Probiotic Blend (50 Billion CFU†) | 500 mg | |
| Lactobacillus acidophilus UALa-01 | ||
| Bacillus subtilis DE111®†† | ||
| Lactobacillus bulgaricus Lb-87 | ||
| Bifidobacterium longum UABI-14 | ||
| Lactobacillus rhamnosus DSM33560 | ||
| Lactobacillus paracasei UALpc-04 | ||
| Bifidobacterium animalis lactis VK2 | ||
| Lactobacillus casei UALc-03 | ||
| Lactobacillus salivarius SD-5851 | ||
| Bifidobacterium lactis BLC1 | ||
| Lactobacillus plantarum UALp-05 | ||
| Streptococcus thermophilus UASt-09 | ||
| 1 The % Daily Value tells you how much a nutrient in a serving of food contributes to a daily diet. 2,000 calories a day is used for general nutrition advise. | ||
If you have a question not answered on this page, please consider submitting it in the Product Questions or Feedback section in the Discussion Forum below.
HiFlora-50₁₂ includes 12 complementary strains and a total of 50 billion CFU† per serving, offering broad support for microbial balance. It also contains a spore-forming Bacillus subtilis strain that remains stable during digestion, which adds durability to the formula.
The typical adult serving is two delayed-release capsules once daily or as directed by a healthcare practitioner. Taking it at a consistent time each day helps maintain steady support for the intestinal environment.
Yes. Storing HiFlora-50₁₂ refrigerated helps maintain viability through the expiration date, and the desiccant-lined bottle provides added protection from moisture.
Adults who want broad, higher-potency daily support for digestive comfort, microbial balance, or periods of lifestyle stress may find this formula helpful. A practitioner can offer guidance based on individual needs.
The formula does not contain milk, eggs, fish, shellfish, peanuts, wheat, or soy. As with any supplement, reviewing the full ingredient list and discussing sensitivities with a practitioner is recommended.
We encourage you to take advantage of these related Wellness Resources on our website.
Osteopathic medicine takes a whole-person view of health, recognizing that the body works as an integrated system capable of healing when supported by steady daily habits. It blends conventional medical training with hands-on techniques that help restore balance, making it especially suited for long-term wellness and preventive care.
Over the last century, everyday eating has shifted from simple, home-prepared meals to a pattern dominated by refined carbohydrates, added sugars, industrial fats, and ultra-processed convenience foods. This shift erodes metabolic health, driving blood sugar swings, inflammation, and nutrient gaps. The result is a steady rise in chronic disease that now touches nearly every family and community.
Over the last century, Americans have moved away from home-cooked meals, daily movement, and predictable rhythms of work and rest. In their place came ultra-processed convenience, sedentary routines, and rising chronic stress. These shifts have quietly reshaped metabolic health and contributed to today's high rates of chronic disease. Understanding how these changes took hold helps explain why so many people now struggle with fatigue, weight gain, and long-term illness.
Metabolic dysfunction often develops quietly &- years before a diagnosis &- undermining energy, mood, weight, and long-term health. This guide clarifies what metabolic dysfunction is, how it differs from metabolic syndrome, and how to restore balance via lifestyle steps and osteopathic principles.
Naturopathic medicine offers a patient-centered, whole-person approach to health that emphasizes the body's natural ability to heal. Instead of managing only symptoms, naturopathic care focuses on identifying root causes and supporting long-term wellness through nutrition, lifestyle changes, and natural therapies.
Reviews are from verified customers who purchased the product on SupplementRelief.com. They are intended to describe the quality and usefulness of the specific product i.e. "how is the product working for you?". Any benefits or results expressed are based on individual experiences that are unique, cannot be guaranteed, and have not been evaluated by the FDA. Consult with your healthcare practitioner to determine if any supplement you are considering purchasing would be a good option for your specific needs.
Not what it's being taken for but it's definitely reducing inflammation systemically.
Expensive but a great supplement that works!
Great pro biotic
Good probiotic to use, love to switch it up every other month
Great product
My functional medicine doctor recommended this product to dear with my intestinal issues. It does work very well and I would order it again if I have that issue again 1
Not a supplement that shows visible results - just hoping it's working.
March 28, 2019 by SupplementRelief:
Typically probiotics don't produce visible results as their role is to increase the good bacteria in the gut to help offset the bad. With improved gut health though you might see reduced bloating and belly fat, particularly as unhealthy carbs and sugars are minimized in the diet.
Since 2010 SupplementRelief.com has provided professional-grade supplements supported by practical wellness content focussed on healthy living, risk reduction, and chronic disease elimination.
SupplementRelief.com promotes a lifestyle of Well-Being with emphasis on whole-foods nutrition, reasonable exercise, stress management, proper sleep, and the use of targeted, high-quality supplements to augment what is missing in our diet. We encourage others to live better through making small, gradual, healthy changes to lifestyle behaviors.
Jay is an original founder of SupplementRelief.com and has provided customer service, managed and operated the business ever since.
We welcome your
call at (888) 424-0032 or
email anytime. We can't always respond immediately but we will at our earliest opportunity. We are even known to respond after hours and on weekends! Learn more about us.
Ask questions. Share your thoughts. Note that we cannot answer questions relating to specific medical conditions - please refer those to your qualified healthcare provider.
Post a new Comment or Reply to an existing one. Help for using the Discussion Forum.
Comments are displayed in order of the last one posted so the most recent one is at the top and the oldest one at the bottom.
Replies within a Comment are displayed in reverse order with the oldest one at the top and the most recent one at the bottom.
Each post identifies
who made the post and the
date and time the post was made.
Mouse over the icons for tooltips that explain what they mean.
If you see this icon you can attach an Audio file to your post.
If you see this icon you can attach a Document file to your post.
If you see this icon you can attach an Image file to your post.
If you see this icon you can attach a Video file to your post.
You will see the
Ban icon (Report Post as SPAM) immediately following the Timestamp of the post. Click this icon if you feel strongly that the content posted is not appropriate and should be reviewed by the Forum Moderator. You will be provided with a confirmation dialog to be sure you wish to submit this post for review. If submitted, the Forum Moderator will be notified to review the post and will determine what type of action to take.
Click
in the upper right corner of this Help modal or anywhere on the web page outside of the modal to exit Help.
Session Expired from Inactivity
Do you want to?
* Disclaimer: This page is available exclusively for SupplementRelief.com clients. None of the information on this website is intended to replace your relationship with your healthcare provider(s). Nothing should be considered medical advice. The information, knowledge, and experience shared on this website are the opinions of SupplementRelief.com. This site and its content are intended to enhance your knowledge base as YOU MAKE YOUR OWN HEALTHCARE DECISIONS in partnership with your qualified health professional.
* These statements have not been evaluated by the Food and Drug Administration. These products and services are not intended to diagnose, treat, cure, or prevent disease.
* There is NO GUARANTEE OF SPECIFIC RESULTS for the products or services offered, and the RESULTS CAN VARY for each individual. Any results claimed by our customers are based on individual experiences that are unique and cannot be guaranteed.
FirstFitness Nutrition and NuMedica may be promoted and sold on the internet ONLY by Authorized Resellers who have been approved by and have registered their website domain with these companies. They strictly prohibit, and actively monitor, the UNAUTHORIZED SALE or RESALE of their products in ALL online public shopping portals including Amazon, eBay, and others and into other countries. All products purchased in SupplementRelief.com are for PERSONAL USE ONLY and CANNOT BE RESOLD to others. Please report violations of Reseller Policy directly to FirstFitness Nutrition at 800.621.4348 and to NuMedica at 800.869.8100.
The content and photographs on this website are copyrighted or Licensed Material and may not be downloaded for other than personal use. Republication, retransmission, reproduction, or any other use of the content or photographs is prohibited. ©2010-2024 SupplementRelief.com.
Are you sure you want to remove this item?